The 22-250 performs better than the 223 caliber.* I would not sell or trade my Remington Model 700 with a Redfield Model 3200 Target scope which is a 20 Power scope.*

If you are doing this on a budget, go with .223. A wide selction of ammo is readily available, as well as rifles with different rates of twist. I would go with a 1 in 9″ twist to be able to shoot up to 69 grain bullets with accuracy. These are good for windier days. On calmer days, you can stick with 55 gr. varmint medicine.

If money is no concern, the 22-250 or .220 Swift are both great choices. Both are faster and flatter shooting than the .223. Also, you are limited to the smaller bullets with these two.

Whichever your choice any of the 3 mentioned are very sound varmint calibers. Personally, I have shot a .223 and .220 Swift extensively and love them equally. Enjoy!

Everyone prefer??? I dont know about that…. Heres the deal. The 22-250 is hands down a superior cartridge over the .223….. But the .223 is still more popular…. Why? It less expensive to shoot…. You can buy .223 in bulk and mil surplus really cheap — This means you can get a lot of practice time in without cleaning your wallet out……. The .223 is excellent for coyote but doesnt have quite the reach of the 22-250…. If the 22-250 is considered a 10 the .223 is a 9…. Plenty enough for long range target shooting and hunting…. 22-250 ammunition generaly starts at $16 a box. .223 can be had on sale for as little as $6 a box…… That is what contributes to it popularity…. I target shoot more than I hunt varmints so prefer the .223…. If you only hunt then the 22-250 is a better choice…

personal opinions will always be argued until the end of time over different cal. rifles,pistols,even shotguns. I like both. 220 Swift is a great cal. to.

Everyone does not, but many do. The .223 is cheaper to shoot when you compare commercial loadings. You will find more rifles chambered in .223 than you will .22-250. If you are only buying commercial ammo, the .22-250 is a faster round. The drawback is that it will wear out your barrel relatively quicker for those shooting thousands of rounds. If you reload, then the cost difference closes up. Some .223 barrels have a quicker barrel twist which allows you to shoot the much heavier and longer bullets if you are reloading.

.22-250 is ballistically superior in every way to the .223. However, not only are there more .223 caliber firearms availiable (ARs, minis etc.) , .223 is significantly cheaper than .22-250.

223 ammo cost less and the military uses it. There are so many different 223 rifles and ammuntion to choose from. 22-250 is more of a limited.

sounds like you answeredc your own question.

Either will do it well.
22-250 will shoot a bit flatter further than .223. Most factory 22-250 loads have a suitable bullets for game killing.. as opposed to surplus .223-5.56 mil spec ammo

If you handload, the .223 can be improved (as any round can) and tailored to your firearm.

Military? yes…as in “5.56 NATO”… You could kill a ‘yote with that FMJ bullet…but I’d rather shoot a soft nosed bullet and get some expansion. FMJ tends to punch on through and cripple smaller animals at times

The rounds are more expensive on the 223, but it’s military.